To extend knowledge of RAI1 function to nonhuman primates, the Huang lab characterized the spatiotemporal distribution and molecular interactions of... Read More
Loss of RAI1 causes Smith-Magenis syndrome (SMS) and as of now, no drugs have been developed to improve neurometabolic phenotypes... Read More
Haploinsufficiency in retinoic acid induced 1 (RAI1) causes Smith-Magenis syndrome (SMS), a severe neurodevelopmental disorder characterized by neurocognitive deficits and... Read More
Supported by SMSRF, Dr. Wei-Hsiang Huang’s team at McGill University studied the function of Rai1, the disease-causing gene of SMS, at different developmental stage.
This comprehensive review article By Dr. Wei-Hsiang Huang summarizes the genetics and clinical features of Autism Spectrum Disorders that are... Read More
Smith-Magenis Syndrome and its Circadian influence on development, behavior, and obesity. June 2015
SMS and Food-Related Behaviors Equivalent to Prader-Willi.
Copy number loss upstream of RAI1 uncovers gene expression regulatory region that may impact Potocki–Lupski syndrome diagnosis- July 2015
Structural Variation Mutagenesis of the Human Genome: Impact on Disease and Evolution -June 2015
Cognitive Phenotypes and Genomic Copy Number Variations in Journal of the American Medical Association - May 2015
