Watch Now: Aaron’s Story

In the most loving and articulate way, SMSRF board member Jennifer Sauer and her husband Brian open up about the challenges and complexities of raising their son Aaron with Smith-Magenis Syndrome (SMS).

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New Style, Same Mission

Introducing SMSRF’s new visual identity designed to blend tradition with innovation.

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New SMS Research Findings

We’re excited to share the latest findings on the RAI1 gene, pivotal in brain development, explored through innovative studies in mice, marmosets, and human cells.

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Exciting News!

SMSRF is thrilled to announce the extension of our research grant with McGill University. Discover how this pivotal partnership is accelerating progress in Smith-Magenis Syndrome research.

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Improving Lives Through Research

We fund only the best, most comprehensive SMS research projects along with the best and brightest scientists focused in this area. Through this science, SMS Research Foundation is committed to improving the lives of children around the world.

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About SMS

Learn more about Smith-Magenis Syndrome and why we’re furthering research to better understand this rare, genetic disease.

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1 in 25,000

…live births in the US are affected by SMS. Identified only in 1982, the SMS Research Foundation is working tirelessly to fund research to improve the treatment options and lives of SMS children.

What is SMS?

Smith-Magenis Syndrome is a complex developmental disorder that affects multiple organ systems of the body. The disorder is characterized by a pattern of abnormalities that are present at birth (congenital) as well as behavioral and cognitive problems.

Our Mission

It is our goal to advance the scientific understanding of this rare syndrome so that effective treatments can be developed to improve the cognitive delays and behavioral issues of those living with SMS.